Bladder Biopsy Post-Op Instructions

  1. After the procedure, you doctor may prescribe an antibiotic. If you do not receive a prescription, prior to leaving the office, please ask your nurse. Make sure that you take the medication as directed. Complete the prescription. Avoid using aspirin for several days to avoid bleeding.
  2. It is normal to have blood in your urine for 3 to 4 days and possibly light rectal bleeding. To clean out the urinary tract drink 1 gallon of fluids during the first 24 hours and then 4-6 glasses (8oz.) of water daily for 2 to 3 days. If you are passing blood clots, call the doctor at 941-309-7000.
  3. It is normal to experience burning on urination for the first 24 hours after the biopsy. If you are having trouble urinating, try to urinate into warm baths. This may alleviate your discomfort.
  4. After the procedure, some men complain of clear to brownish discharge from the penis. You may notice blood in your semen (sperm) for up to 1 month afterward.
  5. If you have nausea, vomiting, shaking, chills, a fever greater than 100 degrees F, or burning on urination after the first 24 hours following the biopsy, call the doctor immediately (day or night) at 941-309-7000.
  6. You should not do any heavy lifting for 24 hours. No straining during bowel movements for 48 hours.
  7. Sexual activity should be avoided for 24-48 hours.
  8. The recovery room nurse will make your follow-up appointment before you leave the center.

Call Your Doctor If at 941-309-7000: 

  • Your temperature rises above 100 degrees F. 
  • You have nausea, vomiting or shaking chills.
  • You are experiencing burning or urination or are passing blood clots.
  • You are unable to urinate when you feel that your bladder is full. 
  • You develop a reaction to your medication such as a skin rash. 


To reduce the risk of infection as noted above, you must complete your entire course of antibiotics, as prescribed by your doctor.